Oncologic Dermatology & Skin Cancer
A skin cancer diagnosis is not a moment for generalist care. It is a moment for the expert who has spent their career at the intersection of dermatologic surgery, oncology, and photodynamic therapy — with the academic depth to match.
Dr. Macrene Alexiades, MD PhD is the recognized world authority on photodynamic therapy (PDT) and the author of Photodynamic Therapy (Elsevier) — the definitive medical reference on a treatment modality that has transformed how skin cancers and pre-cancerous conditions are managed. Her oncologic practice brings that expertise to bear on every patient she sees.
What We Treat & How
Dr. Alexiades provides comprehensive evaluation and management of all forms of skin cancer, including basal cell carcinoma, squamous cell carcinoma, melanoma, and rare cutaneous malignancies. Her practice offers Mohs micrographic surgery — the gold standard for high-risk and facial skin cancers — as well as photodynamic therapy for pre-cancerous lesions and selected malignancies, and complex surgical reconstruction to achieve both complete clearance and optimal cosmetic outcomes.
Conditions & Procedures
– Basal cell and squamous cell carcinoma — all stages and risk profiles
– Melanoma — in situ through advanced disease
– Mohs micrographic surgery and complex reconstruction
– Photodynamic therapy (PDT) — actinic keratoses, superficial BCC, field cancerization
– High-risk patient surveillance programs
– Second opinions on diagnosis and proposed treatment plans
Second Opinions
Patients questioning a prior skin cancer diagnosis or treatment recommendation are welcome to schedule a consultation. Dr. Alexiades will review your pathology, imaging, and clinical history and provide a direct, expert assessment informed by one of the deepest bodies of knowledge in the field. In oncologic dermatology, independent subspecialty verification is not a second guess — it is sound medicine.
G S.
"I've seen Dr. Alexiades several times over the past 5 years and I can't rave enough about how professional and capable she is. She is thoughtful, attentive and has always fully described her recommendations to me. She isn't pushy and won't do procedures that will look 'over done'. A year ago, she noticed an unusual mole and she caught and cured my skin cancer. She's truly the best dermatologist in NYC."
via Healthgrades
H.Z., Stony Brook
"Dr. Alexiades is a warm, caring physician who takes great pride in her profession. I was so lucky to be referred to her during my melanoma journey. She helped save my life. I can't recommend her enough."
via Healthgrades